2014 Research Grant

We are pleased and proud to announce the $20,000

“Maine’s KAT-Walk & Karo-5K Chair of Research”

was one of eleven research grants totaling $230,000 awarded at The 8th Annual Brain Aneurysm Foundation Research Grant Awards Symposium. The event was held on Thursday, September 11, 2014, in Miami, Florida.

Thank you to everyone who supports and donates to the KAT-Walk & Karo-5K to increase Brain Aneurysm awareness and research.

Our 2014 Chair of Research was awarded to Koji Hosaka, PhD, Dept. Neurosurgery, University of Florida, for his research project entitled:

Inflammatory Mediator-Releasing Coil to Promote Cerebral Aneurysm Healing: Modulating Inflammation to Induce Vascular Repair

The purpose of the study is to further investigate previously identified proteins that mediate inflammation in aneurysms. These previously identified proteins that may be involved in aneurysm healing are MCP-1, TNFa, and IL-6. Platinum coils, used in surgery to treat intracranial aneurysm, can conveniently be coated with these proteins to accelerate healing. Coils coated in a single of the three proteins are effective in augmenting healing, but a combination of these proteins may augment it further and shorten healing time. The availability of FDA-approved materials means that translation of successful in vivo treatments into the clinic will be straightforward.

Dr. HosakaKoji Hosaka received his Bachelor of Science degree in Agricultural Biology from Nihon University in Japan in 1999. After obtaining a PhD in Agricultural Biology and Biological Sciences from the same institution in 2004, he came to the University of Florida as a post-doctoral associate in Dr. Edward Scott’s regenerative medicine research group. In 2008, he joined the Department of Neurosurgery and has been an Assistant Scientist within Dr. Brian Hoh’s cerebrovascular research group. His interests include understanding mechanisms of aneurysm formation, aneurysm and vascular repair by bone marrow derived stem cell recruitment, and creation of bioengineered drug eluting neuroendovascular devices
Research Grants

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